EML4-ALK kinase inhibitor 1( EML4 ALK kinase inhibitor 1 )

Catalog No. M26196 CAS No. 1373409-08-5

COA

Datasheet

HNMR

HPLC

MSDS

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Product Name

EML4-ALK kinase inhibitor 1
Note

Research use only, not for human use.
Brief Description

EML4-ALK kinase inhibitor 1 is a potent oral active inhibitor of echinoderm microtubule-associated protein-like 4-anaplastic lymphoma kinase (EML4-ALK), with an IC50 of 1 nM.
Description

EML4-ALK kinase inhibitor 1 is a potent oral active inhibitor of echinoderm microtubule-associated protein-like 4-anaplastic lymphoma kinase (EML4-ALK), with an IC50 of 1 nM.
In Vitro

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In Vivo

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Synonyms

EML4 ALK kinase inhibitor 1
Pathway

Others
Target

Other Targets
Recptor

Lp-PLA2
Research Area

——
Indication

——

CAS Number

1373409-08-5
Formula Weight

580.778
Molecular Formula

C31H48N8O3
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 110 mg/mL (189.41 mM)
SMILES

CCc1nc(C(N)=O)c(Nc2ccc(N3CCC(CC3)N3CCN(C)CC3)c(OC)c2)nc1N[C@H]1CC[C@@H](CC1)OC
Chemical Name

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1.Zehong Wan, et al. Bicyclic pyrimidone compounds. WO2013014185A1.

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